Professor Anne Chang AM

Senior Principal Research Fellow, Head of the Child Health Respiratory Program, Head of the Child and Maternal Health Division

Qualifications:

Bachelor of Medicine and Bachelor of Surgery, University of Melbourne, 1988 (MBBS); Master of Public Health and Tropical Medicine, James Cook University, 2000 (MPHTM); PhD, University of Melbourne, 1998 (PhD); Fellow, Royal Australasian College of Physicians, 1995 (FRACP); Fellow, Thoracic Society of Australia and New Zealand (FThorSoc); Fellow, Asian Pacific Society of Respirology, 2013; Fellow, Australian Academy of Health and Medical Science (FAHMS)

Approved level of HDR supervision at Charles Darwin University:

Principal Supervisor for PhD

Location:

Brisbane, Darwin - Royal Darwin Hospital campus

Biography:

Professor Anne Chang AM is an established leading researcher with international recognition in cough, bronchiectasis and evidence-based medicine (EBM) related to paediatric respiratory medicine. She has helped develop and apply EBM for respiratory illnesses nationally and internationally. She is the editor of two EBM series, one on respiratory medicine and the other on Indigenous health.

Professor Chang is also responsible for changing paradigms in the investigation and management of paediatric cough leading to earlier diagnosis of bronchiectasis, describing a pre-bronchiectasis condition (PBB), the inclusion of respiratory symptoms in primary care child assessments (Northern Territory and Queensland) and the establishment of the first international Indigenous collaborative respiratory study.

Professor Anne Chang AM
Email
Research Themes
  • Child and Maternal Health
  • Respiratory Health

 

  1. Ruffles TJC, Goyal V, Marchant JM, Masters IB, Yerkovich ST, Buntain HM, Cook A, Schultz A, Upham JW, Champion A, Versteegh L, Chang AB. Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. Lancet Respir Med. 2021; 9(10):1121-1129. doi: 10.1016/S2213-2600(21)00104-1.
  2. O'Grady KF, Grimwood K, Torzillo PJ, Rablin S, Lovie-Toon Y, Kaus M, Arnold D, Roberts J, Buntain H, Adsett D, King A, Scott M, Anderson J, Toombs M, Chang AB. Effectiveness of a chronic cough management algorithm at the transitional stage from acute to chronic cough in children: a multi-centre randomised controlled trial. Lancet Child & Adolescent Health 2019;3:889-98
  3. Goyal V, Grimwood K, Ware RS, Byrnes CA, Morris PS, Masters IB, McCallum GB, Binks MJ, Marchant JM, Smith-Vaughan HS, O'Grady KF, Champion A, Buntain H, Schultz A, Chatfield M, Torzillo PJ, Chang AB. Efficacy of oral antibiotics for non-severe exacerbations of bronchiectasis in children (BEST 1): A multi-centre, double-blind, double-dummy, randomised placebo-controlled trial. Lancet Respir Med. 2019; 7(9):791-801. doi: 10.1016/S2213-2600(19)30254-1.
  4. Goyal V, Grimwood K, Byrnes CA, Morris PS, Masters IB, Ware RS, McCallum GB, Binks MJ, Marchant JM, Van Asperen PP, O'Grady KF, Champion A, Buntain H, Petsky H, Torzillo PJ, Chang AB. Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): A multi-centre, double-blind, non-inferiority randomised controlled trial. Lancet 2018;392(10154):1197-1206. doi: 10.1016/S0140-6736(18)31723-9. 
  5. Chang AB, Bush A, Grimwood K. Diagnosis and management of children with bronchiectasis. Lancet 2018 Sep 8;392(10150):866-879. doi: 10.1016/S0140-6736(18)31554-X
  6. Chalmers JD, Chang AB, Chotirmall SJ, Dhar R, McShane PJ. Bronchiectasis. Nature Rev Disease Primers 2018;4(1):45. doi: 10.1038/s41572-018-0042-3
  7. Chang AB, Grimwood K. Antibiotics for childhood pneumonia: do we really know how long to treat? N Engl J Med 2020; 383(1):77-79. doi: 10.1056/NEJMe2016328
  8. Chang AB, Zacharasiewicz A, Goyal V, Boyd J, Alexopoulou E, Aliberti S, Bell L, Bush A, Claydon A, Constant C, Fortescue R, Hill AT, Karadag B, Powell Z, Wilson C, Grimwood K, Kantar A; other members of Child-BEAR-Net. Task Force report: European Respiratory Society statement for defining respiratory exacerbations in children and adolescents with bronchiectasis for clinical trials. Eur Respir J. 2022 Nov 3;60(5):2200300 doi: 10.1183/13993003.00300-2022. 
  9. Chang AB, Fortescue R, Grimwood K, Alexopoulou E, Bell L, Boyd J, Bush A, Chalmers JD, Hill AT, Karadag B, Midulla F, McCallum GB, Powell Z, Snijders D, Song WJ, Tonia T, Wilson C, Zacharasiewicz A, Kantar A. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J 2021: 58(2):2002990. doi: 10.1183/13993003.02990-2020 
  10. de Benedictis FM, Kerem E, Chang AB, Colin AA, Zar HJ, Bush A. Complicated pneumonia in children. Lancet. 2020; 396(10253):786-798.
     

For more publications by Prof. Anne Chang visit: https://researchers.cdu.edu.au/en/persons/anne-chang/publications/

  1. MEDIA RELEASE | Five Menzies researchers awarded NHMRC Investigator Grants

    MEDIA RELEASE | Five Menzies researchers awarded NHMRC Investigator Grants

    Date

    Five researchers from Menzies have been awarded NHMRC Investigator Grants in today’s funding round announcement, totaling more than $9 million.

  2. Researchers at CDU some of the most influential in their fields

    Researchers at CDU some of the most influential in their fields

    Date

    According to a Stanford University study, there were 22 academics from CDU and Menzies School of Health research who ranked in the top two per cent of researchers referenced in their respected disciplines for 2020.

  3. Preventing infant wheeze and childhood asthma

    Preventing infant wheeze and childhood asthma

    Date

    A new $1.6 million Australian-UK world-first project aimed at preventing wheeze in preschool children and potentially asthma in later childhood by using an orally administered bacteria lysate to boost immune systems has been announced.

  4. 2021 Howard Williams Medal winner announced

    2021 Howard Williams Medal winner announced

    Date

    Congratulations to Professor Anne Chang FRACP who has been announced as the 2021 Howard Williams Medal winner.

  5. CDU academics named among world’s most influential

    CDU academics named among world’s most influential

    Date

    Menzies School of Health Research Professor Bart Currie, Professor Anne Chang AM, Professor Ric Price, Associate Professor Steven Tong, Professor Nicholas Anstey, Professor Joshua Davis, Professor Alan Cass, Professor Peter Morris and Professor Amanda Leach

  6. Media alert | Outcomes of protracted bacterial bronchitis in children: A 5‐year prospective cohort study

    Media alert | Outcomes of protracted bacterial bronchitis in children: A 5‐year prospective cohort study

    Date

    Findings from the first prospective longer-term outcome NHMRC-funded study for children with protracted bacterial bronchitis (PBB) in children have identified a link between children with PBB and asthma, highlighting the importance of identifying potentially treatable symptoms in children with chronic respiratory diseases.

  7. Acute lower respiratory infections in Indigenous infants in the NT

    Acute lower respiratory infections in Indigenous infants in the NT

    Date

    Menzies senior research fellow Dr Michael Binks examined acute lower respiratory infection (ALRI) hospital admissions among Indigenous infants in the Northern Territory from 2006 to 2015, across three periods of different pneumococcal conjugate vaccine (PCV) use.

  8. $440 million funding boost for vital health and medical research for all stages of life

    $440 million funding boost for vital health and medical research for all stages of life

    Date

    $6 million in research funding for three Indigenous health grants in the Northern Territory. This includes $2.5 million for an NHMRC Centre of Research Excellence at the Menzies School of Health Research to prevent and manage bronchiectasis, a lung disease which results in recurrent chest infections and is particularly common in Aboriginal and Torres Strait Islander people.

  9. The Lancet | Anne Chang: a champion of childhood lung health

    The Lancet | Anne Chang: a champion of childhood lung health

    Date

    At a health centre in Melbourne for Aboriginal and Torres Strait Islanders in the late 1980s, medical student Anne Chang had her eyes opened to Indigenous disadvantage in Australia

  10. Menzies clinician-researchers receive NHMRC funding

    Menzies clinician-researchers receive NHMRC funding

    Date

    Two Menzies School of Health Research clinician-researchers have secured competitive NHMRC funding to continue their valuable work over the coming years.

  11. $12 Million NT Investment aims to save lives

    $12 Million NT Investment aims to save lives

    Date

    Indigenous Affairs Minister Nigel Scullion and Indigenous Health Minister Ken Wyatt AM today announced the National Health and Medical Research Council (NHMRC) funding for researchers at Darwin’s Menzies School of Medical Research, covering Indigenous-specific and broader health projects.

  12. Evidence informs chronic cough guidelines

    Evidence informs chronic cough guidelines

    Date

    High-quality evidence informs chronic cough guidelines Results from the first multicentre randomised controlled trial on chronic cough in children led by our child health respiratory team were incorporated into the updated American College of Chest...

  13. Red hot Alice puts mums and bubs at risk

    Red hot Alice puts mums and bubs at risk

    Date

    Three Menzies staff - Professor Anne Chang, Dr Gurmeet Singh and Dr Elizabeth McDonald - were involved in this study. The paper, published in the International Journal of Environmental Research and Public Health, linked preterm births with extreme heat.

  14. Menzies leaders inducted into important new health and medical academy

    Menzies leaders inducted into important new health and medical academy

    Date

    Three Menzies researchers inducted as Fellows of the newly formed Australian Academy of Health and Medical Sciences.

  15. NHMRC fellowship snapshot: Professor Anne Chang

    NHMRC fellowship snapshot: Professor Anne Chang

    Date

    Menzies' head of child health Professor Anne Chang was recently awarded a senior practitioner fellowship as part of the National Health and Medical Research Council's yearly multi-million dollar funding round.

  16. Cough, step and jump: a profile of Professor Anne Chang

    Cough, step and jump: a profile of Professor Anne Chang

    Date

    One doctor’s mission to beat childhood lung disease.

  17. Menzies' lung and cancer programs win $5 million in 'research excellence' funding

    Menzies' lung and cancer programs win $5 million in 'research excellence' funding

    Date

    Two esteemed lung health and cancer research programs from the Menzies School of Health Research were today declared ‘Centres for Research Excellence’ and awarded funding of $2.5 million each over five years.